The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2007
Filed:
Aug. 17, 2005
Norman M. Kneteman, Edmonton, CA;
John B. Sacci, Jr., Baltimore, MD (US);
D. Lorne Tyrrell, Edmonton, CA;
John F. Elliott, Edmonton, CA;
Abdu F. Azad, Baltimore, MD (US);
Norman M. Kneteman, Edmonton, CA;
John B. Sacci, Jr., Baltimore, MD (US);
D. Lorne Tyrrell, Edmonton, CA;
John F. Elliott, Edmonton, CA;
Abdu F. Azad, Baltimore, MD (US);
KMT Hepatech, Inc., Edmonton, Alberta, CA;
University of Maryland, Baltimore, Baltimore, MD (US);
Abstract
The present invention features a non-human animal model of malaria, e.g.,, particularly. The model is based on a non-human, immunocompromised transgenic animal having a human-mouse chimeric liver, where the transgene provides for expression of a urokinase-type plasminogen activator in the liver. The invention also features methods for identifying candidate therapeutic agents, e.g., agents having anti-pathogenic activity against malaria.