The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2007
Filed:
Sep. 08, 2003
Substituted bicylic thiophene derivatives, compositions containing such compounds and methods of use
Applicants:
Joseph Duffy, Cranford, NJ (US);
Elizabeth Louise Campbell, North Brunswick, NJ (US);
Rui Liang, East Brunswick, NJ (US);
Zenon Konteatis, Chatham Township, NJ (US);
Inventors:
Joseph Duffy, Cranford, NJ (US);
Elizabeth Louise Campbell, North Brunswick, NJ (US);
Rui Liang, East Brunswick, NJ (US);
Zenon Konteatis, Chatham Township, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4365 (2006.01); A61K 31/381 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention addresses substituted thiophene derivatives, as well as compositions containing such compounds and methods of treatment. The compounds in the present invention are glucagon antagonists. The compounds block the action of glucagon at its receptor and thereby decrease the levels of plasma glucose providing a treatment of diabetes.