The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2007
Filed:
Oct. 15, 2003
Xu Wu, San Diego, CA (US);
Sheng Ding, San Diego, CA (US);
Nathanael S. Gray, San Diego, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Abstract
The present invention provides compositions and methods for differentiating and transdifferentiating mammalian cells into cells of an osteoblast lineage, using compounds of the following formula: wherein Ris a functional group including, for example, Calkyl, Ccycloalkyl, hydroxyl-Calkyl, aryl-Calkyl, substituted with 0-2 Rgroups, and heterocyclo-Calkyl, optionally substituted with Calkyl; Ris hydrogen and Ris a functional group including, for example, halogen, Calkyl, —C(O)—Calkyl, —SO—N(RR), halo—Calkyl, —O-aryl and —N(RR), or when Rand Rare on adjacent ring atoms they are optionally taken together to form —O—(CH)—O—; and all pharmaceutically acceptable salts and hydrates thereof.