The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 25, 2007

Filed:

Oct. 22, 2002
Applicants:

Tasuku Honjo, Kyoto-shi, Kyoto, JP;

Kei Tashiro, Kyoto, JP;

Jun Takahashi, Kyoto, JP;

Hiroki Toda, Palo Alto, CA (US);

Inventors:

Tasuku Honjo, Kyoto-shi, Kyoto, JP;

Kei Tashiro, Kyoto, JP;

Jun Takahashi, Kyoto, JP;

Hiroki Toda, Palo Alto, CA (US);

Assignees:

Ono Pharmaceuticals Co., Ltd., Osaka, JP;

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to human, rat and mouse stem cell-derived neuron survival factor polypeptides (SDNSF), a process for producing them, cDNA encoding SDNSF, a vector comprising the cDNA, host cells transformed by the vector, an antibody against SDNSF, pharmaceutical compositions containing SDNSF or the antibody, a method of assaying SDNSF, a reagent for assaying SDNSF, and a screening method using SDNSF. The polypeptides are effective in the survival of nerve cells and, therefore, efficacious in treating injury to the central nerve system caused by brain infarction, brain hemorrhage, spinal cord injury, etc.


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