The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2007
Filed:
Mar. 01, 2001
Martial Renard, Paris, FR;
Laurent Belkadi, Montrouge, FR;
Patrick England, Paris, FR;
Hugues Bedouelle, Paris, FR;
Martial Renard, Paris, FR;
Laurent Belkadi, Montrouge, FR;
Patrick England, Paris, FR;
Hugues Bedouelle, Paris, FR;
Institut Pasteur, Paris, FR;
Centre National de la Recherche Scientifique-CNRS, Paris, FR;
Abstract
The invention relates to biosensors, methods for obtaining them and their use fro detecting, assaying or locating, in direct immunofluorescence, a ligand such as an antigen or hapten, in a heterogeneous population. The biosensor includes (i) at least one fragment of a receptor which is protein in nature, capable of binding to a ligand via an active site, where at least one amino acid residues of the fragment located in the proximity of said active site is naturally present in the form of a cystein Cys residue, or is substituted with a Cys residue, and (ii) a fluorophore coupled to the Cys residue.