The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2007

Filed:

Feb. 18, 2005
Applicants:

Martin Patrick Allen, Voluntown, CT (US);

Thomas Allen Chappie, Old Lyme, CT (US);

John Michael Humphrey, Mystic, CT (US);

Spiros Liras, Stonington, CT (US);

William Michael Whalen, New London, CT (US);

Inventors:

Martin Patrick Allen, Voluntown, CT (US);

Thomas Allen Chappie, Old Lyme, CT (US);

John Michael Humphrey, Mystic, CT (US);

Spiros Liras, Stonington, CT (US);

William Michael Whalen, New London, CT (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61K 31/4725 (2006.01); C07D 239/94 (2006.01); C07D 217/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention pertains to substituted quinazoline and isoquinoline compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE-10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.


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