The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2007

Filed:

Sep. 21, 2005
Applicants:

Jia Liu, San Diego, CA (US);

Naresh Nayyar, San Diego, CA (US);

Ming Guo, San Diego, CA (US);

Zhen-ping Wu, La Jolla, CA (US);

Bennett Chaplin Borer, San Diego, CA (US);

Aparna Nadig Srirangam, San Diego, CA (US);

Mark Bryan Mitchell, San Diego, CA (US);

Yi LI, San Diego, CA (US);

Jan-jon Chu, Carlsbad, CA (US);

Inventors:

Jia Liu, San Diego, CA (US);

Naresh Nayyar, San Diego, CA (US);

Ming Guo, San Diego, CA (US);

Zhen-Ping Wu, La Jolla, CA (US);

Bennett Chaplin Borer, San Diego, CA (US);

Aparna Nadig Srirangam, San Diego, CA (US);

Mark Bryan Mitchell, San Diego, CA (US);

Yi Li, San Diego, CA (US);

Jan-Jon Chu, Carlsbad, CA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/06 (2006.01); A61K 31/55 (2006.01); A61P 35/00 (2006.01); A61P 35/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to novel polymorphic and amorphous forms of a phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.


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