The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2007
Filed:
Dec. 24, 2003
Nagarajan Ramesh, Sunnyvale, CA (US);
David Frey, Half Moon Bay, CA (US);
Bahram Memarzadeh, San Carlos, CA (US);
Dechao Yu, Foster City, CA (US);
Nagarajan Ramesh, Sunnyvale, CA (US);
David Frey, Half Moon Bay, CA (US);
Bahram Memarzadeh, San Carlos, CA (US);
DeChao Yu, Foster City, CA (US);
Cell Genesys, Inc., South San Francisco, CA (US);
Abstract
Agents and methods for enhancing recombinant virus transduction in the bladder epithelium are described. A first method involves contacting the luminal surface of the bladder with a composition comprising a transduction enhancing agent and an oncolytic virus. Alternatively, the luminal surface of the bladder can be contacted first with a pretreatment composition comprising a transduction enhancing agent and, subsequently, with a composition comprising an oncolytic virus. Bladder treatment compositions comprising a transduction enhancing agent and an oncolytic virus are also described.