The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2007

Filed:

Nov. 07, 2001
Applicants:

Harold G. Craighead, Ithaca, NY (US);

Jun Kameoka, Ithaca, NY (US);

Inventors:

Harold G. Craighead, Ithaca, NY (US);

Jun Kameoka, Ithaca, NY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B32B 5/02 (2006.01); B32B 27/04 (2006.01); B32B 27/12 (2006.01); G01N 21/00 (2006.01); G01N 15/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

A system and method for detecting changes in the refractive index of a fluid in a small test volume. A change in the refractive index can indicate a change in the chemical composition of the fluid. The test volume has a depth comparable to or less than the wavelength of incident light. In one embodiment, an internal surface of the volume is coated with a binding partner selected to bind with a targeted molecule. When the targeted molecule binds to the binding partner, the optical properties of the system change. The refractive index is determined by illuminating the test volume with laser light and measuring transmitted or reflected light.


Find Patent Forward Citations

Loading…