The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2007
Filed:
Mar. 03, 2003
David K. Bol, Gaithersburg, MD (US);
Joan M. Carboni, Yardley, PA (US);
Ronald B. Rowley, Guilford, CT (US);
Tai W. Wong, Belle Meade, NJ (US);
Francis Y. Lee, Yardley, PA (US);
David K. Bol, Gaithersburg, MD (US);
Joan M. Carboni, Yardley, PA (US);
Ronald B. Rowley, Guilford, CT (US);
Tai W. Wong, Belle Meade, NJ (US);
Francis Y. Lee, Yardley, PA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
A transgenic non-human mammal whose germ cells and somatic cells contain a constructively activated tyrosine kinase receptor introduced into the mammal, or an ancestor of the mammal, at an embryonic stage. The transgenic non-human mammals can be used as ligand-independent in vivo models for the identification and development of selective tyrosine kinase modulators for the treatment of cancer.