The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2007

Filed:

Jul. 19, 2002
Applicants:

Richard Evans, Loughborough, GB;

Matthew Perry, Loughborough, GB;

Brian Springthorpe, Loughborough, GB;

Inventors:

Richard Evans, Loughborough, GB;

Matthew Perry, Loughborough, GB;

Brian Springthorpe, Loughborough, GB;

Assignee:

AstraZeneca AB, Södertälje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compounds of formula (I) wherein: T is C(O) or S(O); W is C(O) or S(O); X is CH, O or NH; Y is CRor N; n is 0, 1 or 2; m is 1 or, when Y is CRm is 0; Ris optionally substituted aryl or optionally substituted heterocyclyl; R, R, R,, R, R, Rand Rare, independently, hydrogen or C?1-6#191 alkyl; Ris hydrogen or C-Calkyl; Ris alkyl, optionally substituted aryl, optionally substituted aralkyl or optionally substituted heterocyclyl; and Ris hydrogen or C-Callkyl; that are modulators of chemokine (especially CCR3) activity and are especially useful for treating asthma and/or rhinitis.


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