The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2007

Filed:

Dec. 02, 2002
Applicants:

John S. Babcook, Vancouver, CA;

Ian Foltz, Vancouver, CA;

Chadwick T. King, Vancouver, CA;

Varghese Palathumpat, Fremont, CA (US);

Xiao-dong Yang, Palo Alto, CA (US);

Inventors:

John S. Babcook, Vancouver, CA;

Ian Foltz, Vancouver, CA;

Chadwick T. King, Vancouver, CA;

Varghese Palathumpat, Fremont, CA (US);

Xiao-Dong Yang, Palo Alto, CA (US);

Assignee:

Amgen Fremont Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

Antibodies which specifically recognize the human CD45 isoform RB are presented. These antibodies may be used to block undesirable immune reactions in patients with transplant rejection and autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and autoimmune diabetes. Preferred antibodies are fully human, monoclonal antibodies.


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