The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2007
Filed:
Jul. 05, 2001
Martin Göttlicher, Stutensee, DE;
Thorsten Heinzel, Frankfurt am Main, DE;
Bernd Groner, Frankfurt am Main, DE;
Peter Herrlich, Karlsruhe, DE;
Martin Göttlicher, Stutensee, DE;
Thorsten Heinzel, Frankfurt am Main, DE;
Bernd Groner, Frankfurt am Main, DE;
Peter Herrlich, Karlsruhe, DE;
Georg-Speyter-Haus Chemotherapeutisches Forschungsinstitut, Frankfurt, DE;
Abstract
The present invention relates to the use of the drug valproic acid and derivatives thereof as inhibitors of enzymes having histone deacetylase activity. The invention also relates to the use of those compounds for the manufacture of a medicament for the treatment of diseases which are associated with hypoacetylation of histones or in which induction of hyperacetylation has a beneficial effect for example by induction of differentiation and/or apoptosis in transformed cells.