The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2007

Filed:

Apr. 20, 2005
Applicants:

Dean R. Artis, Kensington, CA (US);

David Y. Jackson, San Bruno, CA (US);

Thomas E. Rawson, Mountain View, CA (US);

Mark E. Reynolds, Millbrae, CA (US);

Daniel P. Sutherlin, South San Francisco, CA (US);

Mark S. Stanley, Pacifica, CA (US);

Inventors:

Dean R. Artis, Kensington, CA (US);

David Y. Jackson, San Bruno, CA (US);

Thomas E. Rawson, Mountain View, CA (US);

Mark E. Reynolds, Millbrae, CA (US);

Daniel P. Sutherlin, South San Francisco, CA (US);

Mark S. Stanley, Pacifica, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/403 (2006.01); C07D 207/04 (2006.01); C07D 209/82 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are compounds of formula (I) wherein A, Q, W, X, Y, Z, Rto R, m and n are as defined herein. Compounds of the invention bind to αintegrin receptors and thereby inhibit binding of ligands for αintegrins which is useful for prophylactic and/or therapeutic treatment of diseases and conditions associated with αintegrins or their ligands.


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