The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2007

Filed:

Aug. 13, 2002
Applicants:

George D. Hartman, Lansdale, PA (US);

Thomas J. Tucker, North Wales, PA (US);

John T. Sisko, Lansdale, PA (US);

Anthony M. Smith, Green Lane, PA (US);

William C. Lumma, Jr., Helena, MO (US);

Inventors:

George D. Hartman, Lansdale, PA (US);

Thomas J. Tucker, North Wales, PA (US);

John T. Sisko, Lansdale, PA (US);

Anthony M. Smith, Green Lane, PA (US);

William C. Lumma, Jr., Helena, MO (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 31/4535 (2006.01); C07D 417/12 (2006.01); C07D 401/12 (2006.01); C07D 277/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals.


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