The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2007
Filed:
Mar. 21, 2002
Applicants:
Robert M. Strieter, Ann Arbor, MI (US);
Steven L. Kunkel, Ann Arbor, MI (US);
Inventors:
Robert M. Strieter, Ann Arbor, MI (US);
Steven L. Kunkel, Ann Arbor, MI (US);
Assignee:
The Regents of The University of Michigan, Ann Arbor, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12P 21/06 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); C12N 15/63 (2006.01); C07K 2/00 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed are various discoveries concerning the angiogenic and angiostatic properties of the CXC chemokines, including the finding that the ELR motif controls the ability of these molecules to induce angiogenesis. Aspects of the invention include, for example, the identification of IP-10, MIG and certain IL-8 analogues as angiostatic agents, and their use in inhibiting angiogenesis in various systems.