The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2007
Filed:
Nov. 22, 2001
Takao Imai, Tokyo, JP;
Akinori Tokunaga, Tokyo, JP;
Tetsu Yoshida, Tokyo, JP;
Katsuhiko Mikoshiba, Tokyo, JP;
Masato Nakafuku, Tokyo, JP;
Hideyuki Okano, Tokyo, JP;
Takao Imai, Tokyo, JP;
Akinori Tokunaga, Tokyo, JP;
Tetsu Yoshida, Tokyo, JP;
Katsuhiko Mikoshiba, Tokyo, JP;
Masato Nakafuku, Tokyo, JP;
Hideyuki Okano, Tokyo, JP;
Japan Science and Technology Corporation, Kawaguchi-shi, JP;
Abstract
An Numb protein expression inhibitor comprising, as active ingredient, Musashi protein, a polypeptide having an amino acid sequence obtained by replacement, deletion, addition or insertion of at least one amino acid in an amino acid sequence of Musashi protein, or a gene encoding said polypeptide. By the present invention, a new function of Musashi protein has been elucidated. Described specifically, Musashi protein inhibits expression of Numb protein having a neuronal differentiation regulating function and potentiates the activity of the Notch signaling system, so that Musashi protein can be used as a therapeutic for various diseases of the central nervous system.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile