The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2007
Filed:
Apr. 24, 2002
Michael A. Blanar, Malvern, PA (US);
Wen-pin Yang, Princeton, NJ (US);
Paul C. Levesque, Yardley, PA (US);
Michael G. Neubauer, Skillman, NJ (US);
Wayne A. Little, Pottstown, PA (US);
Michael A. Blanar, Malvern, PA (US);
Wen-Pin Yang, Princeton, NJ (US);
Paul C. Levesque, Yardley, PA (US);
Michael G. Neubauer, Skillman, NJ (US);
Wayne A. Little, Pottstown, PA (US);
Bristol-Myers Squibb Co., Princeton, NJ (US);
Abstract
The present invention relates to KCNQ proteins defining potassium channels. In particular, the invention concerns the human KCNQ2, human KCNQ3, murine KCNQ2, and rat KCNQ2 proteins reported herein. KCNQ2 and KCNQ3 proteins are nervous system-selective and may be involved in neurotransmission and neuroprotection. The KCNQ2 and KCNQ3 of the present invention can be used to assay for modulators of the proteins, which would be useful in treatment of such disorders as ataxia, myokymia, seizures, Alzheimer's disease, Parkinson's disease, age-associated memory loss, learning deficiencies, motor neuron diseases, epilepsy, stroke, and the like.