The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2007
Filed:
Mar. 10, 2005
Cycloalkyl—containing 5-acylindolinones, the preparation thereof and their use as medicaments
Armin Heckel, Biberach, DE;
Gerald Jürgen Roth, Biberach, DE;
Jörg Kley, Mittelbiberach, DE;
Stefan Hoerer, Ochsenhausen, DE;
Ingo Uphues, Ummendorf, DE;
Armin Heckel, Biberach, DE;
Gerald Jürgen Roth, Biberach, DE;
Jörg Kley, Mittelbiberach, DE;
Stefan Hoerer, Ochsenhausen, DE;
Ingo Uphues, Ummendorf, DE;
Boehringer Ingelheim International GmbH, Ingelheim, DE;
Abstract
The present invention relates to cycloalkyl-containing 5-acylindolinones of general formula wherein Rto Rare defined as in claimsto, the tautomers, the enantiomers, the diastereomers, the mixtures thereof and the salts thereof, which have valuable pharmacological properties, particularly an inhibiting effect on protein kinases, particularly an inhibiting effect on the activity of glycogen synthase kinase (GSK-3).