The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2007
Filed:
May. 24, 2005
Hiromu Habashita, Mishima-gun, JP;
Shin-ichi Hamano, Mishima-gun, JP;
Shiro Shibayama, Mishima-gun, JP;
Yoshikazu Takaoka, Mishima-gun, JP;
Hiromu Habashita, Mishima-gun, JP;
Shin-ichi Hamano, Mishima-gun, JP;
Shiro Shibayama, Mishima-gun, JP;
Yoshikazu Takaoka, Mishima-gun, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
Triazaspiro[5.5]undecane derivatives of the formula (I), quaternary ammonium salts thereof, N-oxides thereof, non-toxic salts thereof, or pharmaceutical compositions comprising them, as active ingredients (wherein Ris formula (II) or formula (III); Ris alkyl or alkynyl etc.; R, Ris H, (substituted) alkyl etc., or Rand Rtogether to form formula (IV); Ris H or alkyl). Therefore the compounds of the formula (I) regulate the effect of chemokine/chemokine receptor, they are used for prevention and treatment of various inflammatory diseases, asthma, atopic dermatitis, urticaria, allergic diseases, nephritis, nephropathy, hepatitis, arthritis or rheumatoid arthritis etc.