The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2007

Filed:

Feb. 15, 2002
Applicants:

Usha Kasid, Rockville, MD (US);

Prafulla Gokhale, Superior, CO (US);

Jin Pei, Arlington, VA (US);

Rajshree Mewani, Arlington, VA (US);

Imran Ahmad, Wadsworth, IL (US);

Anatoly Dritschilo, Bethesda, MD (US);

Aquilur Rahman, Potomac, MD (US);

Inventors:

Usha Kasid, Rockville, MD (US);

Prafulla Gokhale, Superior, CO (US);

Jin Pei, Arlington, VA (US);

Rajshree Mewani, Arlington, VA (US);

Imran Ahmad, Wadsworth, IL (US);

Anatoly Dritschilo, Bethesda, MD (US);

Aquilur Rahman, Potomac, MD (US);

Assignees:

Georgetown University, Washington, DC (US);

NeoPharm, Inc., Waukegan, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A01N 61/00 (2006.01); C12N 15/88 (2006.01); C12Q 1/68 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to the use of oligonucleotide containing cationic liposomal formulations to enhance the efficacy of chemotherapy and/or radiotherapy, particularly as a means to sensitize cancerous tumor tissues to the efficiencies of chemotherapy. This is particularly advantageous in the context of treating raf expressing tumors such as breast, lung, pancreatic and prostate tumors.


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