The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2007
Filed:
Aug. 06, 2004
Use of biscistronic dna constructs for identifying compounds that inhibit ires-dependent translation
Tzong-yuan Wu, Panchiao, TW;
Tsu-an Hsu, Taipei, TW;
Shin-ru Shih, Taoyuan, TW;
Suey-sheng Kao, Taipei, TW;
Tzyy-rong Jinn, Nantou, TW;
Shin-jhan Zeng, Kaohsiung, TW;
Ying-ju Chen, Shinyuan Township, Pingtung County, TW;
Tzong-Yuan Wu, Panchiao, TW;
Tsu-An Hsu, Taipei, TW;
Shin-Ru Shih, Taoyuan, TW;
Suey-Sheng Kao, Taipei, TW;
Tzyy-Rong Jinn, Nantou, TW;
Shin-Jhan Zeng, Kaohsiung, TW;
Ying-Ju Chen, Shinyuan Township, Pingtung County, TW;
Abstract
The present invention relates to use of bicistronic DNA constructs for identifying compounds that inhibits IRES-dependent translation activity of an infectious enterovirus (EV) or encephalomyocarditis virus (EMCV) without affecting CAP-dependent translation activity of a host subject. The compounds thus identified are useful in preparation of a medicament for treating EV or EMCV infection.