The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2007

Filed:

Oct. 21, 2003
Applicants:

Geertruida M. Veldman, Sudbury, MA (US);

Monique V. Davies, Harpswell, ME (US);

Kening Song, Arlington, MA (US);

Neil M. Wolfman, Dover, MA (US);

Kristie Grove Bridges, Maynard, MA (US);

Anne Field, Herts, GB;

Caroline Russell, Herts, GB;

Viia Valge-archer, Cambs, GB;

Inventors:

Geertruida M. Veldman, Sudbury, MA (US);

Monique V. Davies, Harpswell, ME (US);

Kening Song, Arlington, MA (US);

Neil M. Wolfman, Dover, MA (US);

Kristie Grove Bridges, Maynard, MA (US);

Anne Field, Herts, GB;

Caroline Russell, Herts, GB;

Viia Valge-Archer, Cambs, GB;

Assignees:

Wyeth, Madison, NJ (US);

Cambridge Antibody Technology Limited, Cambridge, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C12P 21/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.


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