The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 21, 2007
Filed:
Nov. 12, 2004
Joseph E. Dinchuk, Stockton, NJ (US);
Paul Davies, Wilmington, DE (US);
Qihong Zhao, Princeton, NJ (US);
Percy H. Carter, Princeton, NJ (US);
Kimberly A. Solomon, Landenberg, PA (US);
Peggy Ann Scherle, Media, PA (US);
Joseph E. Dinchuk, Stockton, NJ (US);
Paul Davies, Wilmington, DE (US);
Qihong Zhao, Princeton, NJ (US);
Percy H. Carter, Princeton, NJ (US);
Kimberly A. Solomon, Landenberg, PA (US);
Peggy Ann Scherle, Media, PA (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention relates to a chimeric chemokine receptor comprising two components: a first sequence comprising the N terminus through the last residue of the seven helix TM region of a first chemokine receptor joined with a second sequence comprising the C terminus of a second chemokine receptor extending from the first intracellular residue of the chemokine receptor to the last residue of the chemokine receptor. The chimeric chemokine receptor can be employed in various applications, such as ligand binding and screening assays and signalling assays. The chimeric chemokine receptor can also form a component of a chemokine receptor modulator design program.