The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 2007
Filed:
Oct. 03, 2001
Applicants:
Gilles Piquet, Perosa Canavese, IT;
Luca Barbero, Chivasso, IT;
Silvio Traversa, Palazzo Canavese, IT;
Monica Gatti, Aosta, IT;
Inventors:
Gilles Piquet, Perosa Canavese, IT;
Luca Barbero, Chivasso, IT;
Silvio Traversa, Palazzo Canavese, IT;
Monica Gatti, Aosta, IT;
Assignee:
Ares Trading S.A., Vaumarcus, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method is described for a method for the regioselective liquid-phase pegylation of GRF, which increases the yield of the GRF-PEG conjugate having 1 PEG molecule covalently bound to the e-amino group of Lys. This method is characterized in that the reaction is carried out in a structuring solvent, such as trifluorethanol.