The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2007
Filed:
Jul. 02, 2003
James J. Storhoff, Evanston, IL (US);
Robert L. Letsinger, Bloomington, IN (US);
Susan R. Hagenow, Salem, WI (US);
James J. Storhoff, Evanston, IL (US);
Robert L. Letsinger, Bloomington, IN (US);
Susan R. Hagenow, Salem, WI (US);
Nanosphere, Inc., Northbrook, IL (US);
Abstract
This invention provides polyanionic polymer conjugates containing non-nucleotide polyanionic polymers that are useful in detecting target analytes such as proteins or small molecules. The invention also provides nanoparticles bound to polyanionic polymer conjugates and methods of preparation and use thereof. The polyanionic polymer conjugates have the formula:L-O—[PO—O-Z-O]—PO—O—Xwherein n ranges from 1 to 200; L represents a moiety comprising a functional group for attaching the polyanion polymer to the nanoparticle surface; Z represents a bridging group, and X represents Q, X' or -Q-X′, wherein Q represents a functional group for attaching a recognition probe to the polyanion polymer, and X′ represents a recognition probe.