The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2007
Filed:
Mar. 27, 2002
Hitoshi Harada, Ibaraki, JP;
Masanobu Shinoda, Ibaraki, JP;
Richard Clark, Ibaraki, JP;
Fumiyoshi Matsuura, Ibaraki, JP;
Eita Emori, Ibaraki, JP;
Shunji Kasai, Ibaraki, JP;
Hideki Yoshitomi, Ibaraki, JP;
Kazuto Yamazaki, Ibaraki, JP;
Takashi Inoue, Ibaraki, JP;
Sadakazu Miyashita, Ibaraki, JP;
Taro Hihara, Ibaraki, JP;
Hitoshi Harada, Ibaraki, JP;
Masanobu Shinoda, Ibaraki, JP;
Richard Clark, Ibaraki, JP;
Fumiyoshi Matsuura, Ibaraki, JP;
Eita Emori, Ibaraki, JP;
Shunji Kasai, Ibaraki, JP;
Hideki Yoshitomi, Ibaraki, JP;
Kazuto Yamazaki, Ibaraki, JP;
Takashi Inoue, Ibaraki, JP;
Sadakazu Miyashita, Ibaraki, JP;
Taro Hihara, Ibaraki, JP;
Eisai Co., Ltd., Tokyo, JP;
Abstract
The present invention provides a novel carboxylic acid derivative, a salt thereof or a hydrate of them which is useful as an insulin sensitizer, and a medicament comprising the derivative as the effective ingredient. More specifically, it provides a carboxylic acid compound represented by the formula (I), a salt thereof or a hydrate of them. In the formula, Ar represents a 6- to 14-membered aromatic ring group which may have at least one substituent; R, R, R, R, R, R, Rand Rare the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a Calkyl group or a Calkoxy group; X represents an oxygen atom or a methylene group; Y represents a group represented by the formula (II) or (III): (wherein Z represents a group represented by the formula (IV): (wherein R, R, Rand Rare the same as or different from each other and each represents a hydrogen atom, a halogen atom, a hydroxyl group, a Calkyl group or a Calkoxy group)); m is 0 or 1; and n is 0 or 1.