The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 07, 2007
Filed:
Apr. 06, 2005
Alan J. Hutchison, Madison, CT (US);
Bertrand L. Chenard, Waterford, CT (US);
James G. Tarrant, Hamden, CT (US);
Guiying LI, Branford, CT (US);
Manuka Ghosh, Madison, CT (US);
George P. Luke, Clinton, CT (US);
John M. Peterson, Durham, CT (US);
Wallace C. Pringle, Guilford, CT (US);
Mary-margaret E. O'donnell, Shelton, CT (US);
Kyungae Lee, Newton, MA (US);
Linda M. Gustavson, Ringoes, NJ (US);
Dario Doller, Wallingford, CT (US);
Alan J. Hutchison, Madison, CT (US);
Bertrand L. Chenard, Waterford, CT (US);
James G. Tarrant, Hamden, CT (US);
Guiying Li, Branford, CT (US);
Manuka Ghosh, Madison, CT (US);
George P. Luke, Clinton, CT (US);
John M. Peterson, Durham, CT (US);
Wallace C. Pringle, Guilford, CT (US);
Mary-Margaret E. O'Donnell, Shelton, CT (US);
Kyungae Lee, Newton, MA (US);
Linda M. Gustavson, Ringoes, NJ (US);
Dario Doller, Wallingford, CT (US);
Neurogen Corporation, Branford, CT (US);
Abstract
Compounds of Formula I are provided, in which variables are as described herein: Such compounds may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of metabolic, feeding and sexual disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting MCH receptors (e.g., receptor localization studies).