IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7253154 B1

PDFFull Text
Date of Patent:
Aug. 07, 2007

Filed:

Nov. 14, 2002

Substituted thiazolopyrimidines as xanthine oxidase inhibitors

Applicants:

Shinichi Yoshida, Chiba, JP;

Atsushi Tendo, Saitama, JP;

Kunio Kobayashi, Saitama, JP;

Nobutaka Mochiduki, Chiba, JP;

Tomio Yamakawa, Chiba, JP;

Yoriko Shinohara, Chiba, JP;

Inventors:

Shinichi Yoshida, Chiba, JP;

Atsushi Tendo, Saitama, JP;

Kunio Kobayashi, Saitama, JP;

Nobutaka Mochiduki, Chiba, JP;

Tomio Yamakawa, Chiba, JP;

Yoriko Shinohara, Chiba, JP;

Assignee:

Nippon Chemiphar Co., Ltd., Tokyo, JP;

Attorney:

Reed Smth LLP

Primary Examiner:

Mark L Berch

Assistant Examiner:

Susanna Moore

Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 9/40 (2006.01); A61K 31/519 (2006.01); A61K 31/675 (2006.01); A61P 19/06 (2006.01); C07D 473/28 (2006.01); C07D 473/34 (2006.01); C07D 473/32 (2006.01); C07D 473/30 (2006.01); C07D 473/00 (2006.01); C07D 471/04 (2006.01); C07D 235/02 (2006.01); C07D 277/66 (2006.01); C07D 263/57 (2006.01); A61K 31/522 (2006.01); A61K 31/52 (2006.01); A61K 31/423 (2006.01); A61K 31/4184 (2006.01); A61K 31/428 (2006.01); A61K 31/4188 (2006.01); A61K 31/424 (2006.01); A61K 31/429 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compounds of the following formula (I) or their salts: in which Rrepresents ORor others, in which Ris an alkyl group having 1-8 carbon atoms which may have a substituent or the like; Ris halogen, nitro, cyano, carboxyl, or the like; Ris hydrogen, halogen, hydroxyl, amino, carboxyl, or the like; X is NR, oxygen, or sulfur, in which Ris hydrogen, or an alkyl group having 1-8 carbon atom which may have a substituent; and each of Y and Z is CRor nitrogen, in which Rhas the same meaning as Rabove, and a xanthine oxidase inhibitor containing the compound as an active ingredient.

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