The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2007
Filed:
Apr. 12, 2001
Oskar Axelsson, Malmo, SE;
Jan Henrik Ardenkjaer-larsen, Malmo, SE;
Sven Månsson, Malmo, SE;
Stefan Petersson, Malmo, SE;
Ib Leunbach, Malmo, SE;
Oskar Axelsson, Malmo, SE;
Jan Henrik Ardenkjaer-Larsen, Malmo, SE;
Sven Månsson, Malmo, SE;
Stefan Petersson, Malmo, SE;
Ib Leunbach, Malmo, SE;
GE Healthcare AS, Oslo, NO;
Abstract
The present invention provides a method of MR investigation of a sample, said method comprising: (i) nuclear spin polarizing a high T1 MR imaging agent which contains in its molecular structure at least two hyperpolarisable nuclei within the same molecule, the frequency difference between the two resonance lines from said nuclei, δυ, being dependent upon either the temperature or the pH of said sample; (ii) administering the nuclear spin polarized MR imaging agent to said sample; (iii) exposing said sample to a radiation at a frequency selected to excite nuclear spin transitions in said MR imaging agent; and (iv) detecting and manipulating magnetic resonance signals from said sample using a single-shot RARE acquisition sequence with shifted data acquisition.