The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2007

Filed:

Jul. 26, 2002
Applicants:

Philip L Felgner, Rancho Santa Fe, CA (US);

Jon a Wolff, Madison, WI (US);

Gary H Rhodes, Leucadia, CA (US);

Robert Wallace Malone, Davis, CA (US);

Dennis A. Carson, Del Mar, CA (US);

Inventors:

Philip L Felgner, Rancho Santa Fe, CA (US);

Jon A Wolff, Madison, WI (US);

Gary H Rhodes, Leucadia, CA (US);

Robert Wallace Malone, Davis, CA (US);

Dennis A. Carson, Del Mar, CA (US);

Assignees:

Vical Incorporated, San Diego, CA (US);

Wisconsin Alumni Research Foundation, Madison, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 9/127 (2006.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate. The method can be used to deliver a therapeutic polypeptide to the cells of the vertebrate, to provide an immune response upon in vivo translation of the polynucleotide, to deliver antisense polynucleotides, to deliver receptors to the cells of the vertebrate, or to provide transitory gene therapy.


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