The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 31, 2007

Filed:

May. 28, 2002
Applicants:

Melissa K. Carpenter, Castro Valley, CA (US);

Jerrod J. Denham, San Francisco, CA (US);

Margaret S. Inokuma, San Jose, CA (US);

R. Scott Thies, Pleasanton, CA (US);

Inventors:

Melissa K. Carpenter, Castro Valley, CA (US);

Jerrod J. Denham, San Francisco, CA (US);

Margaret S. Inokuma, San Jose, CA (US);

R. Scott Thies, Pleasanton, CA (US);

Assignee:

Geron Corporation, Menlo Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides populations of neural progenitor cells and differentiated neurons, obtained by culturing pluripotent cells in special growth cocktails. The technology can be used to produce progenitors that proliferate through at least ˜40 doublings, while maintaining the ability to differentiate into a variety of different neural phenotypes, including dopaminergic neurons. The neural progenitors and terminally differentiated neurons of this invention can be generated in large quantities for use in drug screening and the treatment of neurological disorders.


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