The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2007
Filed:
Jul. 03, 2002
Bruce M. Spiegelman, Waban, MA (US);
Guillaume Adelmant, Boston, MA (US);
Pere Puigserver, Brookline, MA (US);
Bruce M. Spiegelman, Waban, MA (US);
Guillaume Adelmant, Boston, MA (US);
Pere Puigserver, Brookline, MA (US);
Dana-Farber Cancer Institute, Boston, MA (US);
Abstract
The invention provides isolated nucleic acid molecules, designated PGC-1and PGC-1nucleic acid molecules, which encode novel isoforms of PGC-1 family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PGC-1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PGC-1 gene has been introduced or disrupted. The invention still further provides isolated PGC-1 proteins, fusion proteins, antigenic peptides and anti-PGC-1 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.