The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2007
Filed:
Oct. 21, 2002
Marco Gentile, L'Aquila, IT;
Cesare Di Palma, L'Aquila, IT;
Maria Candida Cesta, L'Aquila, IT;
Dompé pha.r.ma S.p.A., L′Aqila, IT;
Abstract
A process for the co-precipitation of a substance with a stabilizer therefor, by a gas anti solvent process comprising introducing into a particle formation vessel a supercritical fluid pure or mixed with a modifier; and a solution comprising said substance and said stabilizer dissolved in a solvent; so as said solvent is extracted from the solution by said supercritical fluid and co-precipitation of the substance and stabilizer occurs. The process may be carried out using an apparatus, for example, shown in FIG., comprising a particle formation vessel () and a nozzle () having a central orifice () serving to introduce a solution of the substance and a plurality of outer orifices () serving to carry a flow of supercritical fluid into the particle formation vessel (), such that the solvent is extracted from the solution by the supercritical fluid and precipitation of micron sized particles of the substance/stabilizer occurs.