The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2007
Filed:
Jan. 13, 2006
Applicants:
Paul Kreye, Ingelheim, DE;
Alfons Lenhart, Weiler, DE;
Franz Dietrich Klingler, Griesheim, DE;
Inventors:
Assignee:
Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, DE;
Primary Examiner:
Int. Cl.
CPC ...
C07B 211/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed are processes for preparing levosalbutamol or the pharmacologically acceptable salts thereof on an industrial scale, using asymmetric hydrogenation as the key step and optionally a special sequence of subsequent steps, using rhodium as catalyst and a chiral bidentate phosphine ligand such as (2R, 4R)-4-(dicyclohexylphosphino)-2-(diphenyl-phosphino-methyl)-N-methyl-aminocarbonyl-pyrrolidine as catalyst system.