The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7247703 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 24, 2007

Filed:

Aug. 21, 2003
Applicants:

Martin a Cheever, Mercer Island, WA (US);

Mary L Disis, Renton, WA (US);

Inventors:

Martin A Cheever, Mercer Island, WA (US);

Mary L Disis, Renton, WA (US);

Assignee:

University of Washington, Seattle, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 7/06 (2006.01); A61K 38/08 (2006.01); A61K 38/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for the detection, monitoring and treatment of malignancies in which the HER-2/neu oncogene is associated are disclosed. Detection of specific T cell activation (e.g., by measuring the proliferation of T cells) in response to in vitro exposure to the HER-2/neu protein, or detection of immunocomplexes formed between the HER-2/neu protein and antibodies in body fluid, allows the diagnosis of the presence of a malignancy in which the HER-2/neu oncogene is associated. The present invention also discloses methods and compositions, including peptides, for treating such malignancies.


Find Patent Forward Citations

Cheever, Martin. (2007). Immune reactivity to her-2/neu protein for diagnosis and treatment of malignancies in which the her-2/neu oncogene is associated (U.S. Patent No. 7247703). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7247703

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