The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2007
Filed:
Jan. 12, 2005
Zhenkun MA, Dallas, TX (US);
Yafei Jin, Dallas, TX (US);
Jing LI, Dallas, TX (US);
Charles Z. Ding, Plano, TX (US);
Keith P. Minor, Dallas, TX (US);
Jamie C. Longgood, Carrollton, TX (US);
IN Ho Kim, Flower Mound, TX (US);
Susan Harran, Dallas, TX (US);
Keith Combrink, Fort Worth, TX (US);
Timothy W. Morris, Coppell, TX (US);
Zhenkun Ma, Dallas, TX (US);
Yafei Jin, Dallas, TX (US);
Jing Li, Dallas, TX (US);
Charles Z. Ding, Plano, TX (US);
Keith P. Minor, Dallas, TX (US);
Jamie C. Longgood, Carrollton, TX (US);
In Ho Kim, Flower Mound, TX (US);
Susan Harran, Dallas, TX (US);
Keith Combrink, Fort Worth, TX (US);
Timothy W. Morris, Coppell, TX (US);
Cumbre Pharmaceuticals Inc., Dallas, TX (US);
Abstract
Rifamycin derivatives having antimicrobial activities, including activities against drug-resistant microorganisms are claimed in this invention. The inventive rifamycin derivatives are uniquely designed in that they have a rifamycin moiety covalently linked to a linker group through the C-3 carbon of the rifamycin moiety and the linker is, in turn covalently linked to a therapeutic moiety or antibacterial agent/pharmacophore. The therapeutic moiety can be a quinolone, an oxazolidinone, a macrolide, an aminoglycoside, a tetracycline core or a structure/pharmacophore associated with an antibacterial agent.