The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2007

Filed:

Jun. 22, 2001
Applicants:

Jae Ho Kim, West Bloomfield, MI (US);

Stephen Lawrence Brown, LaSalle, CA;

Paul S. Swerdlow, Farmington Hills, MI (US);

Inventors:

Jae Ho Kim, West Bloomfield, MI (US);

Stephen Lawrence Brown, LaSalle, CA;

Paul S. Swerdlow, Farmington Hills, MI (US);

Assignees:

Henry Ford Health System, Detroit, MI (US);

Wayne State University, Detroit, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/555 (2006.01); A61K 51/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

According to the present invention, there is provided a delivery vehicle including sickle red blood cells carrying a moiety. The moiety can be any type of diagnostic or therapeutic agent. The present invention further provides for a method of diagnosing systemic hypoxia, acidosis, or hypertonicity by administering sickle red blood cells to a patient and detecting the location of the sickle red blood cells. Additionally, the present invention provides for a method of therapeutic treatment of systemic hypoxia, acidosis, or hypertonicity by administering sickle red blood cells to a patient. Further, the present invention provides for a delivery vehicle that specifically localizes or concentrates at systemic hypoxia, acidosis, or hypertonicity areas. The delivery vehicle is used in diagnosing and therapeutically treating these areas of hypoxia, acidosis, or hypertonicity also. The present invention further provides for a method of making the delivery vehicle described herein.


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