The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2007
Filed:
Dec. 19, 2003
Chengzhi Cai, Houston, TX (US);
Chi Ming Yam, Stafford, TX (US);
Zhongdang Xiao, Nanjing, CN;
Jianhua Gu, Houston, TX (US);
Chengzhi Cai, Houston, TX (US);
Chi Ming Yam, Stafford, TX (US);
Zhongdang Xiao, Nanjing, CN;
Jianhua Gu, Houston, TX (US);
The University of Houston, Houston, TX (US);
Abstract
The present invention provides for a practical method of grafting oligo- and/or poly(ethyleneglycol) (OEG and/or PEG) derivatives onto hydrogen-terminated silicon surfaces, including the surfaces of silicon scanning probe microscopy (SPM) tips, by hydrosilylation of OEG and/or PEG-terminated alkenes. This invention is related to the development of silicon-based bio-devices, including biochips, biosensors such as SPM probes, microarrays, micro-fluidic systems, and implantable microdevices. This invention is also a practical method to modify (many) SPM probe tips with OEG/PEG derivatives and to subsequently modify the tip apex with functional single molecules to improve the specificity and resolution of AFM imaging and measurements. The functional molecules include the dendritic adsorbates with a functional group at their focal point and with or without a tripod-shaped framework.