The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 2007

Filed:

Mar. 05, 2003
Applicants:

Jan G. J. Van DE Winkel, Zeist, NL;

Marcus A. Van Dijk, Bilthoven, NL;

Janine Schuurman, Amsterdam, NL;

Arnout F. Gerritsen, Bunnik, NL;

Ole Baadsgaard, Malmo, SE;

Jørgen Peterson, Rungsted Kyst, DK;

Inventors:

Jan G. J. van de Winkel, Zeist, NL;

Marcus A. van Dijk, Bilthoven, NL;

Janine Schuurman, Amsterdam, NL;

Arnout F. Gerritsen, Bunnik, NL;

Ole Baadsgaard, Malmo, SE;

Jørgen Peterson, Rungsted Kyst, DK;

Assignee:

Genmab A/S, , DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

Isolated human monoclonal antibodies which specifically bind to IL-15 (e.g., human IL-15), and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced in a transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.


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