The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 24, 2007
Filed:
Aug. 25, 2003
Takatomo Sasaki, Suita, JP;
Yusuke Mori, Suita, JP;
Masashi Yoshimura, Suita, JP;
Hiroaki Adachi, Suita, JP;
Hiroshi Masuhara, Suita, JP;
Youichiroh Hosokawa, Suita, JP;
Kazufumi Takano, Suita, JP;
Takatomo Sasaki, Suita, JP;
Yusuke Mori, Suita, JP;
Masashi Yoshimura, Suita, JP;
Hiroaki Adachi, Suita, JP;
Hiroshi Masuhara, Suita, JP;
Youichiroh Hosokawa, Suita, JP;
Kazufumi Takano, Suita, JP;
Osaka Industrial Promotion Organization, Osaka, JP;
Abstract
The present invention relates to a process for producing high-quality crystals of protein or organic substances easily and efficiently. A solution of protein or an organic substance is prepared and then is cooled slowly to be supersaturated to a low degree. This supersaturated solution is irradiated with a femtosecond laser. A local explosion phenomenon occurs at the focal point of the laser and thereby a crystalline nucleus is generated. A high-quality crystal is obtained when a crystal is grown on the crystalline nucleus over a long period of time. The femtosecond laser to be used herein can be a titanium:sapphire laser having a wavelength of 800 nm, a duration of 120 fs, a frequency of 1 kHz, and an output of 400 mW.