The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2007
Filed:
Jul. 27, 2001
Toru Kimura, Kusatsu, JP;
Kaoru Kikuchi, Takarazuka, JP;
Kazuo Kumagai, Sanda, JP;
Nobuo Hosotani, Nishinomiya, JP;
Akiyoshi Kishino, Suita, JP;
Toru Kimura, Kusatsu, JP;
Kaoru Kikuchi, Takarazuka, JP;
Kazuo Kumagai, Sanda, JP;
Nobuo Hosotani, Nishinomiya, JP;
Akiyoshi Kishino, Suita, JP;
Dainippon Sumitomo Pharma Co., Ltd., Osaka, JP;
Abstract
To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic disease and a neurodegenerative disease containing said nerve regeneration promoter, or the like. A low-molecular weight compound, which acts at a concentration of 10 μg/ml or below to inhibit the growth cone collapse activity of semaphorin such as semaphorin 3A, semaphorin 6C or the like and/or the nerve outgrowth inhibitory activity of semaphorin in a collagen gel and which does not substantially affect cell proliferation, is obtained from the culture of strain SPF-3059 belonging to the genus. The low-molecular weight compound with the semaphorin inhibitory activity thus obtained exhibits the in vivo nerve-regeneration promoting action.