The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2007

Filed:

Jun. 12, 2006
Applicants:

David Michael Blum, Upper Saddle River, NJ (US);

Yanzhong Wu, Bardonia, NY (US);

Jean Schmid, Chester, NY (US);

Timothy John Doyle, Morristown, NJ (US);

Jay Thomas Afragola, Spring Valley, NY (US);

Inventors:

David Michael Blum, Upper Saddle River, NJ (US);

Yanzhong Wu, Bardonia, NY (US);

Jean Schmid, Chester, NY (US);

Timothy John Doyle, Morristown, NJ (US);

Jay Thomas Afragola, Spring Valley, NY (US);

Assignee:

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4965 (2006.01); C07D 403/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides 6-chloro-5-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-2-pyrazin-2-yl-N-[(1S)-2,2,2-trifluoro-1-methylethyl]pyrimidin-4-amine hemifumarate which is a tubulin inhibitor useful in the treatment of cancer and processes of making hemifumarate compounds and compositioning of the present invention.


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