The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2007
Filed:
Sep. 22, 2004
Wouter I. Iwema Bakker, Weesp, NL;
Gustaaf J. M. Van Scharrenburg, Weesp, NL;
Adrianus Van Den Hoogenband, Weesp, NL;
Andrew C. Mccreary, Weesp, NL;
Wouter I. Iwema Bakker, Weesp, NL;
Gustaaf J. M. Van Scharrenburg, Weesp, NL;
Adrianus Van Den Hoogenband, Weesp, NL;
Andrew C. McCreary, Weesp, NL;
Solvay Pharmaceuticals B.V., Weesp, NL;
Abstract
The invention relates to hexahydro-pyrido[1,2-a]pyrazine derivatives having interesting neurokinin-NKreceptor antagonistic activity. The invention also relates to methods for the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these compounds as an active ingredient, as well as to the use of these compositions for the treatment of disorders in which neurokinin receptors are involved. The invention relates to compounds represented by the general formula (1) wherein the symbols have the meanings as given in the description.