The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 17, 2007

Filed:

May. 16, 2001
Applicants:

Brigitte Gicquel, Paris, FR;

Denis Portnoï, Paris, FR;

Eng-mong Lim, Paris, FR;

Vladimir Pelicic, Paris, FR;

Agnès Guigueno, Arras, FR;

Yves Goguet DE LA Salmoniere, Paris, FR;

Inventors:

Brigitte Gicquel, Paris, FR;

Denis Portnoï, Paris, FR;

Eng-Mong Lim, Paris, FR;

Vladimir Pelicic, Paris, FR;

Agnès Guigueno, Arras, FR;

Yves Goguet De La Salmoniere, Paris, FR;

Assignee:

Institut Pasteur, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12N 15/63 (2006.01); C12N 15/70 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention concerns recombinant vectors replicated in mycobacteria, a set of sequences coding for exported polypeptides detected by fusion with alkaline phosphatase, in particular one polypeptide, called DP428, of about 12 kD corresponding to an exported protein found in mycobacteria belonging to thecomplex. The invention also concerns methods and kits for detecting in vitro the presence of aand in particular abelonging to thecomplex in a biological sample using said polypeptides, their fragments or polynucleotides coding for the latter. The invention also concerns immunogenic or vaccine compositions for preventing and/or treating infections caused by mycobacteria and in particular abelonging to said complex, particularly tuberculosis.


Find Patent Forward Citations

Loading…