The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2007
Filed:
Jun. 06, 2003
Bruno Frey, Penzberg, DE;
Britta Villbrandt, Braunschweig, DE;
Dietmar Schomburg, Erftstadt, DE;
Harald Sobek, Penzberg, DE;
Waltraud Ankenbauer, Penzberg, DE;
Bruno Frey, Penzberg, DE;
Britta Villbrandt, Braunschweig, DE;
Dietmar Schomburg, Erftstadt, DE;
Harald Sobek, Penzberg, DE;
Waltraud Ankenbauer, Penzberg, DE;
Roche Diagnostics GmbH, MAnnheim, DE;
Abstract
The invention concerns polymerase chimeras which are composed of amino acid fragments representing domains and which combine properties of naturally occurring polymerases that are advantageous with regard to a particular application. It has surprisingly turned out that the domains from the various enzymes are active in the chimeras and exhibit cooperative behavior. In addition the present invention concerns a process for the production of the chimeras according to the invention and the use of these chimeras for the synthesis of nucleic acids e.g. during a polymerase chain reaction. Moreover the present invention concerns a kit which contains the polymerase chimeras according to the invention.