The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2007
Filed:
Aug. 27, 2001
Applicants:
Sang Ki Rhee, Seoul, KR;
Hyun Ah Kana, Taejeon, KR;
Bong Hyun Chung, Taejeon, KR;
Su Min Ko, Kyunggi-do, KR;
Inventors:
Sang Ki Rhee, Seoul, KR;
Hyun Ah Kana, Taejeon, KR;
Bong Hyun Chung, Taejeon, KR;
Su Min Ko, Kyunggi-do, KR;
Assignee:
Dong Kook Pharmaceutical Co., Ltd., Seoul, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/16 (2006.01); C12N 1/19 (2006.01); C12N 15/81 (2006.01); C07K 14/635 (2006.01);
U.S. Cl.
CPC ...
Abstract
Novelmutant strains are provided for producing human parathyroid hormone. The novel strains acre genetically disrupted in at least one of the genes encoding the yapsin family of proteases Yapsin 1, Yapsin 2 and Yapsin 3 and harbor a human parathyroid hormone gene in their genomes. Culturing the novel strains results in the secretion of intact hPTH into culture media at high yield.