The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 17, 2007
Filed:
Oct. 23, 2002
Arnon Chait, Bay Village, OH (US);
Lawrence Delucas, Birmingham, AL (US);
Brad Stoops, Bay Village, OH (US);
Alexander Belgovskiy, Cleveland, OH (US);
Arnon Chait, Bay Village, OH (US);
Lawrence DeLucas, Birmingham, AL (US);
Brad Stoops, Bay Village, OH (US);
Alexander Belgovskiy, Cleveland, OH (US);
UAB Research Foundation, Birmingham, AL (US);
Abstract
A method of screening solution conditions suitable for the crystallization of macromolecules with a picogram to a microgram of protein using picoliter or nanoliter volumes is provided. A preferred method comprises preparing a plurality of recipe solutions in milliliter volumes, aspirating protein and recipe solutions, respectively, from a plurality of wells, and dispensing the protein and recipe solutions into a plurality of wells, covering the combined protein and recipe solutions with oil, and maintaining the solution wells until crystallization or precipitation occur therein.