The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 10, 2007

Filed:

Dec. 10, 2004
Applicants:

Jerome P. Horwitz, Farmington Hills, MI (US);

Stuart T. Hazeldine, Taylor, MI (US);

Thomas H. Corbett, Grosse Point Park, MI (US);

Lisa Polin, Oak Park, MI (US);

Inventors:

Jerome P. Horwitz, Farmington Hills, MI (US);

Stuart T. Hazeldine, Taylor, MI (US);

Thomas H. Corbett, Grosse Point Park, MI (US);

Lisa Polin, Oak Park, MI (US);

Assignee:

Wayne State University, Detroit, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides compounds of formula I: wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.


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