The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2007
Filed:
Dec. 09, 2004
Matthias Mentzel, Hannover, DE;
Dania B. Reiche, Hannover, DE;
Reinhard Brückner, Hannover, DE;
Samuel David, Hannover, DE;
Bartholomeus J. Van Steen, Hannover, DE;
Uwe Schön, Hannover, DE;
Daniel Jasserand, Hannover, DE;
Ulf Preuschoff, Hannover, DE;
Matthias Mentzel, Hannover, DE;
Dania B. Reiche, Hannover, DE;
Reinhard Brückner, Hannover, DE;
Samuel David, Hannover, DE;
Bartholomeus J. Van Steen, Hannover, DE;
Uwe Schön, Hannover, DE;
Daniel Jasserand, Hannover, DE;
Ulf Preuschoff, Hannover, DE;
Solvay Pharmaceuticals GmbH, Hanover, DE;
Abstract
The invention relates to a group of hydronopol derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these novel hydronopol derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which ORL1 receptors are involved. The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description.